Ethyl 3-amino-4,4,4-trifluorocrotonate
97%
Reagent
Code: #181579
Alias
Ethyl 3-amino-4,4,4-trifluorobutenoate
CAS Number
372-29-2
blur_circular Chemical Specifications
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Molecular Information
Weight
183.13 g/mol
Formula
C₆H₈F₃NO₂
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Registry Numbers
MDL Number
MFCD00068195
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Physical Properties
Melting Point
26°C
Boiling Point
83 °C15 mm Hg(lit.)
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Storage & Handling
Density
1.245 g/mL at 25 °C(lit.)
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals, this compound enables the introduction of a trifluoromethyl group into larger molecules, enhancing metabolic stability and bioavailability. Its reactivity allows for the formation of heterocyclic structures common in drug development. It is particularly valuable in creating novel active ingredients in medicinal chemistry due to the unique electronic and steric properties imparted by the trifluoromethyl moiety. Additionally, it serves in research settings for developing new synthetic routes involving fluorinated building blocks.
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