(E)-Methyl 3-(2-(trifluoromethyl)phenyl)acrylate
95%
Reagent
Code: #181159
CAS Number
157518-53-1
blur_circular Chemical Specifications
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Molecular Information
Weight
230.18 g/mol
Formula
C₁₁H₉F₃O₂
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Registry Numbers
MDL Number
MFCD04973007
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Physical Properties
Boiling Point
254.9±35.0 °C(Predicted)
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Storage & Handling
Density
1.251±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules with antifungal, anti-inflammatory, or herbicidal properties. Its α,β-unsaturated ester structure makes it suitable for Michael addition reactions and other conjugate additions in organic synthesis. Commonly employed in medicinal chemistry for constructing trifluoromethyl-substituted aromatic compounds, which can enhance metabolic stability and lipophilicity in drug candidates. Also utilized in the preparation of liquid crystals and functional materials due to the electron-withdrawing nature of the trifluoromethyl group.
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