tert-butyl4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butanoate

97%

Reagent Code: #244547
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CAS Number 2435783-77-8

science Other reagents with same CAS 2435783-77-8

blur_circular Chemical Specifications

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Weight 473.48 g/mol
Formula C₂₃H₂₇N₃O₈
badge Registry Numbers
MDL Number MFCD31630743
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly PROTACs (Proteolysis Targeting Chimeras). It links E3 ligase ligands to target protein binders, enabling selective degradation of disease-related proteins. Its structure supports the formation of bifunctional molecules that recruit cereblon E3 ubiquitin ligase, leading to ubiquitination and subsequent degradation of specific cellular proteins by the proteasome. Commonly applied in the development of anticancer agents and treatments for inflammatory and neurodegenerative diseases.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿57,940.00
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tert-butyl4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butanoate
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Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly PROTACs (Proteolysis Targeting Chimeras). It links E3 ligase ligands to target protein binders, enabling selective degradation of disease-related proteins. Its structure supports the formation of bifunctional molecules that recruit cereblon E3 ubiquitin ligase, leading to ubiquitination and subsequent degradation of specific cellular proteins by the proteasome. Commonly applied in the development of anticancer agents and treatments for inflammatory and neurodegenerative diseases.
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