3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)phenol
98%
Reagent
Code: #244439
CAS Number
1256944-93-0
science Other reagents with same CAS 1256944-93-0
blur_circular Chemical Specifications
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Molecular Information
Weight
288.07 g/mol
Formula
C₁₃H₁₆BF₃O₃
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Registry Numbers
MDL Number
MFCD16994399
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Storage & Handling
Storage
Room temperature
description Product Description
Used primarily in organic synthesis as a building block for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical development. Its boronate ester group facilitates coupling with aryl or vinyl halides under palladium catalysis, making it valuable for constructing complex fluorinated aromatic compounds. The presence of a trifluoromethyl group enhances lipophilicity and metabolic stability in target molecules, which is advantageous in drug design. Commonly employed in the synthesis of bioactive molecules and functional materials where fluorinated scaffolds are required.
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