Trifluoromethylthio-iodine(III)reagent(TFTI)

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Reagent Code: #244378
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CAS Number 2242898-13-9

science Other reagents with same CAS 2242898-13-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 389.13 g/mol
Formula C₁₀H₇F₃INO₂S
inventory_2 Storage & Handling
Storage 2-8°C, avoiding light

description Product Description

Widely used in organic synthesis, this reagent enables efficient trifluoromethylthiolation of various substrates, introducing the SCF₃ group into molecules. The introduction of this group is highly valued in medicinal chemistry due to its strong electron-withdrawing nature and high lipophilicity, which can improve the metabolic stability and membrane permeability of drug candidates. It is particularly useful for late-stage functionalization of complex molecules, allowing the modification of pharmaceuticals and biologically active compounds without extensive synthetic redesign. Its application extends to the preparation of agrochemicals and functional materials where enhanced chemical stability and unique electronic properties are required. The reagent operates under mild conditions and shows good selectivity, making it suitable for use in sensitive transformations.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,920.00
inventory 250mg
10-20 days ฿9,960.00
inventory 1g
10-20 days ฿30,550.00
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Trifluoromethylthio-iodine(III)reagent(TFTI)
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Widely used in organic synthesis, this reagent enables efficient trifluoromethylthiolation of various substrates, introducing the SCF₃ group into molecules. The introduction of this group is highly valued in medicinal chemistry due to its strong electron-withdrawing nature and high lipophilicity, which can improve the metabolic stability and membrane permeability of drug candidates. It is particularly useful for late-stage functionalization of complex molecules, allowing the modification of pharmaceutica

Widely used in organic synthesis, this reagent enables efficient trifluoromethylthiolation of various substrates, introducing the SCF₃ group into molecules. The introduction of this group is highly valued in medicinal chemistry due to its strong electron-withdrawing nature and high lipophilicity, which can improve the metabolic stability and membrane permeability of drug candidates. It is particularly useful for late-stage functionalization of complex molecules, allowing the modification of pharmaceuticals and biologically active compounds without extensive synthetic redesign. Its application extends to the preparation of agrochemicals and functional materials where enhanced chemical stability and unique electronic properties are required. The reagent operates under mild conditions and shows good selectivity, making it suitable for use in sensitive transformations.

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