Trifluoromethylthio-iodine(III)reagent(TFTI)
98%
science Other reagents with same CAS 2242898-13-9
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description Product Description
Widely used in organic synthesis, this reagent enables efficient trifluoromethylthiolation of various substrates, introducing the SCF₃ group into molecules. The introduction of this group is highly valued in medicinal chemistry due to its strong electron-withdrawing nature and high lipophilicity, which can improve the metabolic stability and membrane permeability of drug candidates. It is particularly useful for late-stage functionalization of complex molecules, allowing the modification of pharmaceuticals and biologically active compounds without extensive synthetic redesign. Its application extends to the preparation of agrochemicals and functional materials where enhanced chemical stability and unique electronic properties are required. The reagent operates under mild conditions and shows good selectivity, making it suitable for use in sensitive transformations.
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