1-[3-(Trifluoromethyl)phenylsulfonyl]-L-proline
96%
Reagent
Code: #244333
CAS Number
251096-97-6
science Other reagents with same CAS 251096-97-6
blur_circular Chemical Specifications
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Molecular Information
Weight
323.29 g/mol
Formula
C₁₂H₁₂F₃NO₄S
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Registry Numbers
MDL Number
MFCD00172809
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and anti-inflammatory compounds. Its structure supports conformational rigidity and enhanced metabolic stability, making it valuable in optimizing drug candidates for improved bioavailability and target selectivity. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the electron-withdrawing trifluoromethylphenylsulfonyl group that influences binding affinity and pharmacokinetic properties.
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