(1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)boronicacid
96%
science Other reagents with same CAS 1256345-68-2
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description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronic acid functionality enables formation of carbon-carbon bonds with aryl or heteroaryl halides, facilitating the construction of complex pyrazole-containing structures. The tetrahydropyranyl (THP) group acts as a protecting group for the pyrazole nitrogen, improving stability and solubility during reaction sequences, and can be easily removed under mild acidic conditions when needed. This compound is valuable in medicinal chemistry for developing kinase inhibitors, anti-inflammatory agents, and other therapeutic targets where pyrazole scaffolds are prevalent.
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