1-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazol-1-yl)ethanone
98%
Reagent
Code: #244225
CAS Number
1256359-07-5
science Other reagents with same CAS 1256359-07-5
blur_circular Chemical Specifications
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Molecular Information
Weight
286.13 g/mol
Formula
C₁₅H₁₉BN₂O₃
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Registry Numbers
MDL Number
MFCD12032487
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Physical Properties
Boiling Point
438.8±37.0 °C(Predicted)
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Storage & Handling
Density
1.16±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used primarily as an intermediate in pharmaceutical synthesis, especially in the preparation of kinase inhibitors for cancer treatment. Its boronate ester group enables Suzuki-Miyaura cross-coupling reactions, allowing efficient formation of carbon-carbon bonds in complex molecules. Commonly employed in the development of targeted therapies, including those for leukemia and solid tumors. Also utilized in research settings for the synthesis of novel bioactive compounds and in medicinal chemistry for lead optimization.
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