3-(Trimethylsilyl)propiolaldehyde diethyl acetal

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Reagent Code: #244191
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CAS Number 87219-80-5

science Other reagents with same CAS 87219-80-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 200.35 g/mol
Formula C₁₀H₂₀O₂Si
badge Registry Numbers
MDL Number MFCD08275372
thermostat Physical Properties
Boiling Point 170-172 °C
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as a versatile intermediate in organic synthesis, particularly in the preparation of functionalized alkynes and conjugated systems. Its aldehyde acetal group provides stability while allowing selective deprotection under mild acidic conditions, enabling controlled chain elongation in multi-step syntheses. The trimethylsilyl-protected alkyne moiety facilitates Sonogashira coupling reactions, making it valuable in the construction of complex molecules such as pharmaceuticals, agrochemicals, and advanced materials. It is also employed in the synthesis of natural products and bioactive compounds where alkyne functionality serves as a key structural or reactive element.

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Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿6,050.00
inventory 25g
10-20 days ฿21,700.00
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3-(Trimethylsilyl)propiolaldehyde diethyl acetal
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Used as a versatile intermediate in organic synthesis, particularly in the preparation of functionalized alkynes and conjugated systems. Its aldehyde acetal group provides stability while allowing selective deprotection under mild acidic conditions, enabling controlled chain elongation in multi-step syntheses. The trimethylsilyl-protected alkyne moiety facilitates Sonogashira coupling reactions, making it valuable in the construction of complex molecules such as pharmaceuticals, agrochemicals, and advanced materials. It is also employed in the synthesis of natural products and bioactive compounds where alkyne functionality serves as a key structural or reactive element.
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