(3-((Trifluoromethyl)thio)phenyl)methanamine
97%
Reagent
Code: #244133
CAS Number
234450-33-0
science Other reagents with same CAS 234450-33-0
blur_circular Chemical Specifications
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Molecular Information
Weight
207.22 g/mol
Formula
C₈H₈F₃NS
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Registry Numbers
MDL Number
MFCD00236344
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Storage & Handling
Storage
2-8°C, Sealed, Dry, Light-proof, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents and antidepressants. Its trifluoromethylthio group enhances lipophilicity and metabolic stability, making it valuable in drug design for improving blood-brain barrier penetration. Also employed in agrochemicals to create pesticides and herbicides due to the electron-withdrawing nature of the trifluoromethylthio moiety, which can increase bioavailability and environmental stability. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize lead compounds.
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