3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile
97%
Reagent
Code: #244097
CAS Number
878194-93-5
science Other reagents with same CAS 878194-93-5
blur_circular Chemical Specifications
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Molecular Information
Weight
230.07 g/mol
Formula
C₁₂H₁₅BN₂O₂
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Registry Numbers
MDL Number
MFCD08458477
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Storage & Handling
Storage
2-8°C, sealed, dry, inert gas
description Product Description
Used primarily in cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient Suzuki-Miyaura coupling, allowing for the formation of biaryl and heteroaryl structures commonly found in bioactive molecules. The nitrile group adds further functionality, enabling additional transformations such as hydrolysis to carboxylic acids or reduction to amines. It is especially valuable in medicinal chemistry for constructing complex nitrogen-containing heterocycles with high selectivity and yield.
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