2-(Tetrahydro-2H-Pyran-2-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2H-Indazole
97%
Reagent
Code: #243999
CAS Number
1146955-35-2
science Other reagents with same CAS 1146955-35-2
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Molecular Information
Weight
328.21 g/mol
Formula
C₁₈H₂₅BN₂O₃
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Storage & Handling
Storage
Room temperature
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to construct complex indazole-based scaffolds. These scaffolds are common in drug discovery for their biological activity, including kinase inhibition and anti-inflammatory properties. The boronate ester group enables coupling with aryl halides, allowing rapid diversification of molecular structures during lead optimization. Commonly applied in the development of oncology and CNS-targeted therapeutics. Stable and compatible with a range of reaction conditions, making it valuable in late-stage functionalization.
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