Tert-Butyl (2-(2-(2-(2-((2-(2,6-Dioxopiperidin-3-Yl)-1,3-Dioxoisoindolin-4-Yl)Amino)Ethoxy)Ethoxy)Ethoxy)Ethyl)Carbamate
95%
Reagent
Code: #243887
CAS Number
2204246-03-5
science Other reagents with same CAS 2204246-03-5
blur_circular Chemical Specifications
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Molecular Information
Weight
548.59 g/mol
Formula
C₂₆H₃₆N₄O₉
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Storage & Handling
Storage
Room temperature
description Product Description
Used in pharmaceutical synthesis as a protected intermediate, particularly in the development of targeted protein degraders like PROTACs. Its structure enables conjugation to linker systems for bifunctional molecules, where the tert-butyl carbamate (Boc) group provides amine protection during multi-step reactions. The polyethylene glycol (PEG) spacer enhances solubility and flexibility, improving pharmacokinetic properties in drug candidates. Commonly applied in oncology research for constructing cereblon E3 ligase modulators linked to target-binding moieties.
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