Tert-Butyl N-(2-((4-(4-(3-Bromo-4-Fluorophenyl)-5-Oxo-4,5-Dihydro-1,2,4-Oxadiazol-3-Yl)-1,2,5-Oxadiazol-3-Yl)Amino)Ethyl)Sulfamoylcarbamate
97%
Reagent
Code: #243676
CAS Number
1204669-69-1
science Other reagents with same CAS 1204669-69-1
blur_circular Chemical Specifications
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Molecular Information
Weight
564.34 g/mol
Formula
C₁₇H₁₉BrFN₇O₇S
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Storage & Handling
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly PROTACs (Proteolysis Targeting Chimeras). It links E3 ligase ligands to target protein binders, enabling selective degradation of disease-related proteins. Its tert-butyl carbamate (Boc) protected amine allows for controlled deprotection and further coupling in multi-step syntheses. The sulfamoylcarbamate group enhances solubility and stability, making it suitable for optimizing pharmacokinetic properties in drug development. Commonly applied in oncology and neurodegenerative disease research where protein knockdown is critical.
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