Used as a reagent in organic synthesis for the introduction of the trifluoromethylthio group (SCF₃), which is highly valued in pharmaceutical and agrochemical industries due to its strong electron-withdrawing properties and high lipophilicity. It enables efficient trifluoromethylthiolation of various substrates such as aryl halides, alkenes, and carbonyl compounds under mild conditions. Its high reactivity and selectivity make it suitable for late-stage functionalization in drug discovery, where the SCF₃ group can improve metabolic stability and membrane permeability of bioactive molecules. Also employed in the development of novel fluorinated materials and in radiochemistry for labeling applications.