3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzonitrile
98%
Reagent
Code: #243533
CAS Number
479411-95-5
science Other reagents with same CAS 479411-95-5
blur_circular Chemical Specifications
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Molecular Information
Weight
297.09 g/mol
Formula
C₁₄H₁₅BF₃NO₂
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Registry Numbers
MDL Number
MFCD12405369
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in drug discovery and development. The presence of a nitrile and trifluoromethyl group enhances its utility in creating bioactive molecules with improved metabolic stability and binding affinity. It is particularly useful in the preparation of fluorinated aromatic compounds, which are common motifs in modern medicinal chemistry.
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