1-(2,2,2-Trifluoroacetyl)indoline-5-sulfonyl chloride
97%
Reagent
Code: #243449
CAS Number
210691-38-6
science Other reagents with same CAS 210691-38-6
blur_circular Chemical Specifications
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Molecular Information
Weight
313.68 g/mol
Formula
C₁₀H₇ClF₃NO₃S
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Registry Numbers
MDL Number
MFCD09261241
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals and agrochemicals. Its sulfonyl chloride group enables easy attachment to amines or alcohols, forming sulfonamides or sulfonate esters, which are common motifs in drug design. The trifluoroacetyl group enhances electrophilicity and can act as a protecting group or be further transformed. It is especially valuable in the development of kinase inhibitors and other targeted therapies due to its ability to improve metabolic stability and binding affinity. Also employed in peptide modification and labeling due to its selective reactivity under mild conditions.
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