1-(2,2,2-Trifluoroacetyl)indoline-5-sulfonyl chloride

97%

Reagent Code: #243449
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CAS Number 210691-38-6

science Other reagents with same CAS 210691-38-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 313.68 g/mol
Formula C₁₀H₇ClF₃NO₃S
badge Registry Numbers
MDL Number MFCD09261241
inventory_2 Storage & Handling
Storage 2-8°C, Inert Gas

description Product Description

Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals and agrochemicals. Its sulfonyl chloride group enables easy attachment to amines or alcohols, forming sulfonamides or sulfonate esters, which are common motifs in drug design. The trifluoroacetyl group enhances electrophilicity and can act as a protecting group or be further transformed. It is especially valuable in the development of kinase inhibitors and other targeted therapies due to its ability to improve metabolic stability and binding affinity. Also employed in peptide modification and labeling due to its selective reactivity under mild conditions.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,440.00
inventory 250mg
10-20 days ฿9,220.00
inventory 1g
10-20 days ฿26,420.00

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1-(2,2,2-Trifluoroacetyl)indoline-5-sulfonyl chloride
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Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals and agrochemicals. Its sulfonyl chloride group enables easy attachment to amines or alcohols, forming sulfonamides or sulfonate esters, which are common motifs in drug design. The trifluoroacetyl group enhances electrophilicity and can act as a protecting group or be further transformed. It is especially valuable in the development of kinase inhibitors and other targeted therapies due to its ability to improve metabolic stability and binding affinity. Also employed in peptide modification and labeling due to its selective reactivity under mild conditions.
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