(4-((Tetrahydro-2H-pyran-2-yl)methoxy)phenyl)boronic acid
98%
Reagent
Code: #243288
CAS Number
1313761-97-5
science Other reagents with same CAS 1313761-97-5
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Molecular Information
Weight
236.07 g/mol
Formula
C₁₂H₁₇BO₄
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Registry Numbers
MDL Number
MFCD12080515
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Storage & Handling
Storage
Room temperature, inert gas
description Product Description
Used in organic synthesis as a building block for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical development. The boronic acid group reacts with aryl halides in the presence of a palladium catalyst to construct biaryl frameworks commonly found in bioactive molecules. The tetrahydropyranyl (THP) protecting group stabilizes the ether functionality during reaction sequences and can be removed under mild acidic conditions when needed. This compound is particularly valuable in medicinal chemistry for assembling complex aromatic structures with high selectivity and functional group tolerance.
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