trimethyl(2-tetrahydropyran-4-ylethynyl)silane
95%
Reagent
Code: #243187
CAS Number
1604039-54-4
science Other reagents with same CAS 1604039-54-4
blur_circular Chemical Specifications
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Molecular Information
Weight
182.34 g/mol
Formula
C₁₀H₁₈OSi
thermostat
Physical Properties
Boiling Point
209.0±29.0 °C(Predicted)
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Storage & Handling
Density
0.90±0.1 g/cm3(Predicted)
Storage
Room temperature, dry
description Product Description
Used as a silyl protecting group reagent in organic synthesis, particularly in the construction of complex molecules such as natural products and pharmaceuticals. The tetrahydropyran (THP) moiety enhances solubility and stability during reaction sequences, while the ethynyl linker allows for further functionalization via click chemistry or cross-coupling reactions. Its primary role is to mask reactive functional groups, especially alcohols or alkynes, during multistep syntheses, and it can be selectively removed under mild acidic conditions without affecting other sensitive groups in the molecule. This makes it valuable in the development of fine chemicals and bioactive compounds.
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