tert-butyl (2,2-difluoro-1-(o-tolyl)cyclopropyl)carbamate
95%
Reagent
Code: #242123
blur_circular Chemical Specifications
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Molecular Information
Weight
283.14 g/mol
Formula
C₁₅H₁₉F₂NO₂
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Storage & Handling
Storage
2-8℃
description Product Description
Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research. Its structure supports the development of cyclopropane-containing analogs that enhance metabolic stability and binding affinity in drug candidates. Commonly employed in the preparation of protease inhibitors and receptor modulators due to the steric bulk and electronic properties of the difluorocyclopropyl group. The tert-butyl carbamate (Boc) protecting group allows for controlled amine reactivity during multi-step synthesis, making it valuable in medicinal chemistry for building complex molecules with high selectivity.
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