trans-1-(tert-butoxycarbonyl)-4-(3,5-difluorophenyl)pyrrolidine-3-carboxylic acid
98%
science Other reagents with same CAS 1329835-75-7
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure supports the construction of complex drug candidates by enabling selective functionalization and coupling reactions. Commonly employed in medicinal chemistry for optimizing potency and metabolic stability in small-molecule therapeutics. The Boc-protected amine and carboxylic acid functionalities allow for sequential deprotection and amide bond formation, making it valuable in solid-phase and solution-phase peptide-like synthesis. Also utilized in the preparation of protease inhibitors and central nervous system-active compounds due to its conformationally constrained pyrrolidine core and fluorinated aryl group, which enhance target binding and bioavailability.
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