trans-1-(tert-butoxycarbonyl)-4-(3,5-difluorophenyl)pyrrolidine-3-carboxylic acid

98%

Reagent Code: #241896
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CAS Number 1329835-75-7

science Other reagents with same CAS 1329835-75-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 327.33 g/mol
Formula C₁₆H₁₉F₂NO₄
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure supports the construction of complex drug candidates by enabling selective functionalization and coupling reactions. Commonly employed in medicinal chemistry for optimizing potency and metabolic stability in small-molecule therapeutics. The Boc-protected amine and carboxylic acid functionalities allow for sequential deprotection and amide bond formation, making it valuable in solid-phase and solution-phase peptide-like synthesis. Also utilized in the preparation of protease inhibitors and central nervous system-active compounds due to its conformationally constrained pyrrolidine core and fluorinated aryl group, which enhance target binding and bioavailability.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿9,650.00
inventory 1g
10-20 days ฿30,960.00
inventory 100mg
10-20 days ฿6,300.00

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trans-1-(tert-butoxycarbonyl)-4-(3,5-difluorophenyl)pyrrolidine-3-carboxylic acid
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Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure supports the construction of complex drug candidates by enabling selective functionalization and coupling reactions. Commonly employed in medicinal chemistry for optimizing potency and metabolic stability in small-molecule therapeutics. The Boc-protected amine and carboxylic acid functionalities allow for sequential deprotection and amide

Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure supports the construction of complex drug candidates by enabling selective functionalization and coupling reactions. Commonly employed in medicinal chemistry for optimizing potency and metabolic stability in small-molecule therapeutics. The Boc-protected amine and carboxylic acid functionalities allow for sequential deprotection and amide bond formation, making it valuable in solid-phase and solution-phase peptide-like synthesis. Also utilized in the preparation of protease inhibitors and central nervous system-active compounds due to its conformationally constrained pyrrolidine core and fluorinated aryl group, which enhance target binding and bioavailability.

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