tert-butyl (trans-2-(2,4,6-trifluorophenyl)cyclopropyl)carbamate
99%
Reagent
Code: #241799
blur_circular Chemical Specifications
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Molecular Information
Weight
287.28 g/mol
Formula
C₁₄H₁₆F₃NO₂
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Storage & Handling
Storage
2-8℃
description Product Description
Used in pharmaceutical synthesis as a protected amine intermediate, particularly in the development of biologically active compounds. Its cyclopropyl structure with fluorinated aromatic ring enhances metabolic stability and lipophilicity, making it valuable in medicinal chemistry for optimizing drug candidates. The tert-butyl carbamate (Boc) group allows for selective protection during multi-step synthesis, enabling controlled reactions in peptide-like frameworks or heterocyclic systems. Commonly employed in the preparation of enzyme inhibitors and receptor modulators where fluorinated motifs improve binding affinity and pharmacokinetic properties.
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