3-(4-((tert-butyldimethylsilyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

98%

Reagent Code: #241765

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 374.512 g/mol
Formula C₁₉H₂₆N₂O₄Si
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used in pharmaceutical synthesis as an intermediate in the development of targeted protein degradation therapies, particularly in the design of PROTACs (proteolysis-targeting chimeras). Its structure enables linkage between E3 ubiquitin ligase ligands and target protein binders, facilitating selective degradation of disease-related proteins. Commonly employed in research for oncology and neurodegenerative disease drug discovery due to its stability and modifiable functional groups. Also utilized in solid-phase synthesis and medicinal chemistry optimization for improved pharmacokinetic properties.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,386.00
inventory 250mg
10-20 days ฿5,040.00
inventory 1g
10-20 days ฿10,080.00

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3-(4-((tert-butyldimethylsilyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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Used in pharmaceutical synthesis as an intermediate in the development of targeted protein degradation therapies, particularly in the design of PROTACs (proteolysis-targeting chimeras). Its structure enables linkage between E3 ubiquitin ligase ligands and target protein binders, facilitating selective degradation of disease-related proteins. Commonly employed in research for oncology and neurodegenerative disease drug discovery due to its stability and modifiable functional groups. Also utilized in solid

Used in pharmaceutical synthesis as an intermediate in the development of targeted protein degradation therapies, particularly in the design of PROTACs (proteolysis-targeting chimeras). Its structure enables linkage between E3 ubiquitin ligase ligands and target protein binders, facilitating selective degradation of disease-related proteins. Commonly employed in research for oncology and neurodegenerative disease drug discovery due to its stability and modifiable functional groups. Also utilized in solid-phase synthesis and medicinal chemistry optimization for improved pharmacokinetic properties.

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