Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate
95%
Reagent
Code: #184626
CAS Number
228728-08-3
science Other reagents with same CAS 228728-08-3
blur_circular Chemical Specifications
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Molecular Information
Weight
361.11 g/mol
Formula
C₁₂H₉FINO₃
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Registry Numbers
MDL Number
MFCD12922926
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of potent antimicrobial agents. Its structure allows for further functionalization at the quinoline core, enabling the creation of derivatives with enhanced activity against resistant bacterial strains. Commonly employed in pharmaceutical research to optimize drug candidates targeting DNA gyrase and topoisomerase IV enzymes. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to improve pharmacokinetic properties and reduce toxicity in next-generation antibiotics.
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