ethyl (E)-3-(2-(trifluoromethyl)phenyl)acrylate
96%
Reagent
Code: #183792
CAS Number
376641-48-4
science Other reagents with same CAS 376641-48-4
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Molecular Information
Weight
244.21 g/mol
Formula
C₁₂H₁₁F₃O₂
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Storage & Handling
Storage
2-8℃
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of compounds with anti-inflammatory and antifungal properties. Its α,β-unsaturated ester structure makes it valuable in Michael addition reactions and other carbon-carbon bond-forming processes in organic synthesis. Commonly employed in medicinal chemistry for constructing trifluoromethyl-substituted aromatic frameworks, which can enhance metabolic stability and lipophilicity in drug candidates. Also utilized in the preparation of specialty polymers and functional materials where fluorinated moieties improve thermal and chemical resistance.
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