Ethyl Di-o-tolylphosphonoacetate
95%
science Other reagents with same CAS 188945-41-7
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description Product Description
Used as a key reagent in organic synthesis, particularly in Horner-Wadsworth-Emmons (HWE) olefination reactions, enabling the efficient formation of carbon-carbon double bonds. Its stabilized phosphonate group facilitates the generation of α,β-unsaturated esters and other olefinic compounds with high stereoselectivity. Commonly applied in the synthesis of complex molecules such as pharmaceuticals, agrochemicals, and natural products where precise control over alkene geometry is required. The presence of o-tolyl groups enhances steric and electronic properties, improving reaction yields and selectivity in challenging transformations.
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