4-Ethoxycarbonyl-2-nitrobenzeneboronic Acid (contains varying amounts of Anhydride)

≥98%(HPLC)

Reagent Code: #183068
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CAS Number 5785-70-6

science Other reagents with same CAS 5785-70-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 238.99 g/mol
Formula C₉H₁₀BNO₆
badge Registry Numbers
MDL Number MFCD02179460
thermostat Physical Properties
Melting Point 125°C
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used primarily in organic synthesis as a building block for pharmaceuticals and agrochemicals, this compound serves as a key reagent in Suzuki-Miyaura cross-coupling reactions. Its boronic acid functionality enables the formation of carbon-carbon bonds, especially in the construction of biaryl systems found in active pharmaceutical ingredients. The presence of a nitro group allows for further functionalization, such as reduction to an amine, enabling diversification of molecular structure. The ethoxycarbonyl group acts as an electron-withdrawing moiety, influencing reactivity and regioselectivity in coupling processes. Commonly employed in medicinal chemistry for lead optimization, it supports the rapid assembly of complex aromatic frameworks. Due to its sensitivity to moisture, it is often handled with care or used in situ where the anhydride form may also participate in controlled reactions.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿1,380.00
inventory 250mg
10-20 days ฿520.00
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4-Ethoxycarbonyl-2-nitrobenzeneboronic Acid (contains varying amounts of Anhydride)
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Used primarily in organic synthesis as a building block for pharmaceuticals and agrochemicals, this compound serves as a key reagent in Suzuki-Miyaura cross-coupling reactions. Its boronic acid functionality enables the formation of carbon-carbon bonds, especially in the construction of biaryl systems found in active pharmaceutical ingredients. The presence of a nitro group allows for further functionalization, such as reduction to an amine, enabling diversification of molecular structure. The ethoxycarb

Used primarily in organic synthesis as a building block for pharmaceuticals and agrochemicals, this compound serves as a key reagent in Suzuki-Miyaura cross-coupling reactions. Its boronic acid functionality enables the formation of carbon-carbon bonds, especially in the construction of biaryl systems found in active pharmaceutical ingredients. The presence of a nitro group allows for further functionalization, such as reduction to an amine, enabling diversification of molecular structure. The ethoxycarbonyl group acts as an electron-withdrawing moiety, influencing reactivity and regioselectivity in coupling processes. Commonly employed in medicinal chemistry for lead optimization, it supports the rapid assembly of complex aromatic frameworks. Due to its sensitivity to moisture, it is often handled with care or used in situ where the anhydride form may also participate in controlled reactions.

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