4-Ethoxycarbonyl-2-nitrobenzeneboronic Acid (contains varying amounts of Anhydride)
≥98%(HPLC)
science Other reagents with same CAS 5785-70-6
blur_circular Chemical Specifications
description Product Description
Used primarily in organic synthesis as a building block for pharmaceuticals and agrochemicals, this compound serves as a key reagent in Suzuki-Miyaura cross-coupling reactions. Its boronic acid functionality enables the formation of carbon-carbon bonds, especially in the construction of biaryl systems found in active pharmaceutical ingredients. The presence of a nitro group allows for further functionalization, such as reduction to an amine, enabling diversification of molecular structure. The ethoxycarbonyl group acts as an electron-withdrawing moiety, influencing reactivity and regioselectivity in coupling processes. Commonly employed in medicinal chemistry for lead optimization, it supports the rapid assembly of complex aromatic frameworks. Due to its sensitivity to moisture, it is often handled with care or used in situ where the anhydride form may also participate in controlled reactions.
shopping_cart Available Sizes & Pricing
Cart
No products