Ethyl 4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxylate
95%
science Other reagents with same CAS 1080026-94-3
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description Product Description
Ethyl 4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxylate is a key intermediate in the synthesis of Pramipexole, a non-ergoline dopamine agonist used for treating Parkinson's disease and restless legs syndrome. It functions as a building block for pharmaceuticals targeting central nervous system dopaminergic pathways, particularly D2 and D3 receptors. The bicyclic thienopyridine core with the ethyl carboxylate substituent enables selective modifications to optimize receptor affinity, pharmacokinetics, and blood-brain barrier penetration. Widely used in medicinal chemistry for structure-activity relationship (SAR) studies and development of novel CNS therapeutics.
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