Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate

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Reagent Code: #181793
label
Alias (R)-(-)-4-cyano-3-hydroxybutyrate (R)-4-cyano-3-hydroxybutyrate ethyl 4-cyano-3-hydroxybutyrate side chain ATS-5
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CAS Number 141942-85-0

science Other reagents with same CAS 141942-85-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 157.17 g/mol
Formula C₇H₁₁NO₃
badge Registry Numbers
MDL Number MFCD00270839
thermostat Physical Properties
Boiling Point 270 °C(lit.)
inventory_2 Storage & Handling
Density 1.114 g/mL at 25 °C(lit.)
Storage 2~8°C, dry, sealed

description Product Description

Used as a key chiral intermediate in the synthesis of statin-class cholesterol-lowering drugs, particularly atorvastatin and rosuvastatin. Its enantiomerically pure structure enables efficient construction of the pharmacologically active side chain in these medications. The hydroxyl and cyano functional groups allow for selective chemical transformations, making it valuable in multi-step pharmaceutical manufacturing. Its ester group aids in solubility and reactivity during coupling reactions. Widely utilized in asymmetric synthesis due to high stereochemical purity, ensuring the final drug product has the desired biological activity and safety profile.

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Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿174.00
inventory 25g
10-20 days ฿460.00
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Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate
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Used as a key chiral intermediate in the synthesis of statin-class cholesterol-lowering drugs, particularly atorvastatin and rosuvastatin. Its enantiomerically pure structure enables efficient construction of the pharmacologically active side chain in these medications. The hydroxyl and cyano functional groups allow for selective chemical transformations, making it valuable in multi-step pharmaceutical manufacturing. Its ester group aids in solubility and reactivity during coupling reactions. Widely utilized in asymmetric synthesis due to high stereochemical purity, ensuring the final drug product has the desired biological activity and safety profile.
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