Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate
97%
Reagent
Code: #181793
Alias
(R)-(-)-4-cyano-3-hydroxybutyrate (R)-4-cyano-3-hydroxybutyrate ethyl 4-cyano-3-hydroxybutyrate side chain ATS-5
CAS Number
141942-85-0
science Other reagents with same CAS 141942-85-0
blur_circular Chemical Specifications
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Molecular Information
Weight
157.17 g/mol
Formula
C₇H₁₁NO₃
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Registry Numbers
MDL Number
MFCD00270839
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Physical Properties
Boiling Point
270 °C(lit.)
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Storage & Handling
Density
1.114 g/mL at 25 °C(lit.)
Storage
2~8°C, dry, sealed
description Product Description
Used as a key chiral intermediate in the synthesis of statin-class cholesterol-lowering drugs, particularly atorvastatin and rosuvastatin. Its enantiomerically pure structure enables efficient construction of the pharmacologically active side chain in these medications. The hydroxyl and cyano functional groups allow for selective chemical transformations, making it valuable in multi-step pharmaceutical manufacturing. Its ester group aids in solubility and reactivity during coupling reactions. Widely utilized in asymmetric synthesis due to high stereochemical purity, ensuring the final drug product has the desired biological activity and safety profile.
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