Ethyl trimethylsilylacetate is an organosilicon compound used as a reagent in organic synthesis, particularly for nucleophilic additions to carbonyl groups. It generates the enolate equivalent of ethyl acetate, enabling the formation of β-hydroxy esters or, via Peterson olefination, α,β-unsaturated esters after elimination of the trimethylsilyl group. This makes it valuable for constructing carbon-carbon bonds in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It also serves as a building block for silylated intermediates, enhancing reactivity and selectivity in multi-step reactions.