Used in research as a potent and selective antagonist of the orexin OX2 receptor, showing potential in the study of sleep disorders such as insomnia. Demonstrates high brain penetration and oral bioavailability in preclinical models, making it a valuable tool compound for investigating the role of orexin signaling in regulating wakefulness and sleep architecture. Has been utilized in pharmacological studies to differentiate OX2 receptor-mediated effects from OX1 receptor activity, aiding in the development of targeted therapies for narcolepsy and other hypersomnolent conditions.