Entinostat (MS-275)
10mM in DMSO
Reagent
Code: #181336
CAS Number
209783-80-2
science Other reagents with same CAS 209783-80-2
blur_circular Chemical Specifications
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Molecular Information
Weight
376.41 g/mol
Formula
C₂₁H₂₀N₄O₃
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Registry Numbers
MDL Number
MFCD03453552
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in cancer research, particularly for its potential in treating solid tumors and hematological malignancies. It functions as a histone deacetylase (HDAC) inhibitor, which helps reactivate silenced tumor suppressor genes. Often studied in combination with other therapies such as hormone therapy, immunotherapy, or chemotherapy to enhance anti-tumor effects. Shows promise in breast cancer, especially in combination with aromatase inhibitors. Also under investigation for use in lung cancer, melanoma, and leukemia due to its ability to modulate gene expression and promote cancer cell differentiation and apoptosis.
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