Used as an activated carbonate reagent in organic synthesis for the efficient formation of carbamates by reacting with amines. The N-hydroxysuccinimide (NHS) group facilitates selective coupling under mild conditions, making it valuable in peptide synthesis, bioconjugate preparation, and the introduction of linker groups. The (E)-cyclooctenyl moiety acts as a traceless or cleavable linker in solid-phase synthesis or targeted delivery systems, owing to the alkene functionality that enables further modifications such as olefin metathesis or hydrogenation. Its stability across various solvents and controlled reactivity support its application in multi-step sequences with orthogonal protection strategies.