9,10-Dihydrobenzo[α]pyrene-7(8H)-one
97%
Reagent
Code: #180188
CAS Number
3331-46-2
science Other reagents with same CAS 3331-46-2
blur_circular Chemical Specifications
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Molecular Information
Weight
270.32 g/mol
Formula
C₂₀H₁₄O
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Registry Numbers
MDL Number
MFCD00003601
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used primarily in research settings as a metabolic intermediate in studies of polycyclic aromatic hydrocarbon (PAH) metabolism. It serves as a model compound for investigating the biochemical transformation and detoxification pathways of carcinogenic PAHs in biological systems. Commonly employed in in vitro assays to evaluate enzyme activity, particularly cytochrome P450-mediated oxidation, and to assess the formation of reactive metabolites that may bind to DNA. Also utilized in environmental toxicology to understand the metabolic activation of PAHs found in pollutants such as cigarette smoke, vehicle exhaust, and charred foods. Its structure helps researchers probe structure-activity relationships in mutagenicity and carcinogenicity testing.
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