Used as a key reagent in organic synthesis, particularly in the preparation of fluorinated analogs of biologically active compounds. Its structure allows for the introduction of difluoroalkyl and aryl iodide functionalities, making it valuable in pharmaceutical research for developing new drug candidates. The phosphonate group enables Horner-Wadsworth-Emmons reactions, facilitating the formation of carbon-carbon double bonds with high stereoselectivity. It is also employed in the synthesis of fluorinated building blocks for medicinal chemistry and agrochemicals, where the presence of fluorine can enhance metabolic stability and bioavailability.