2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-yloxy)isoindoline-1,3-dione

98%

Reagent Code: #179481
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CAS Number 2226303-74-6

science Other reagents with same CAS 2226303-74-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 312.28 g/mol
Formula C₁₆H₁₂N₂O₅
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. It plays a critical role in the development of PROTACs (proteolysis-targeting chimeras), which are bifunctional molecules designed to induce the degradation of disease-causing proteins. Its alkyne functional group allows for efficient conjugation via click chemistry, enabling rapid assembly of complex drug candidates. Due to its ability to engage cereblon, it is widely utilized in oncology and immunology drug discovery programs, especially in the creation of novel anticancer agents with improved selectivity and potency.

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Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿11,400.00

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2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-yloxy)isoindoline-1,3-dione
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Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. It plays a critical role in the development of PROTACs (proteolysis-targeting chimeras), which are bifunctional molecules designed to induce the degradation of disease-causing proteins. Its alkyne functional group allows for efficient conjugation via click chemistry, enabling rapid assembly of complex drug candidates. Due to its

Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. It plays a critical role in the development of PROTACs (proteolysis-targeting chimeras), which are bifunctional molecules designed to induce the degradation of disease-causing proteins. Its alkyne functional group allows for efficient conjugation via click chemistry, enabling rapid assembly of complex drug candidates. Due to its ability to engage cereblon, it is widely utilized in oncology and immunology drug discovery programs, especially in the creation of novel anticancer agents with improved selectivity and potency.

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