2-(2,6-Dioxo-3-piperidinyl)-4-ethynyl-1H-isoindole-1,3(2H)-dione
98%
science Other reagents with same CAS 2412439-20-2
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description Product Description
Used primarily as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in targeted protein degradation therapies, such as PROTACs (proteolysis-targeting chimeras). It is also employed in the preparation of anticancer agents due to its role in promoting the degradation of disease-related proteins. Widely utilized in medicinal chemistry research for designing small molecules with enhanced specificity and potency.
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