Used as an activating agent in peptide synthesis, facilitating the coupling of amino acids by enhancing reactivity of carboxyl groups. Commonly employed in the preparation of complex organic molecules where selective and efficient esterification or amidation is required. Its sulfonate-based structure improves solubility and stability in aprotic solvents, making it suitable for use in multi-step syntheses of pharmaceuticals and bioactive compounds. Often chosen for its ability to minimize racemization during activation of sensitive substrates.