(Difluoromethyl)triphenylphosphonium bromide
97%
science Other reagents with same CAS 58310-28-4
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Used as a reagent in organic synthesis, particularly for the introduction of difluoromethyl groups into organic molecules. This phosphonium salt enables the formation of difluoromethylated compounds through Wittig-type reactions, which are valuable in medicinal chemistry for modifying the metabolic stability, lipophilicity, and bioavailability of drug candidates. It is especially useful in the development of fluorinated pharmaceuticals and agrochemicals where the difluoromethylene group acts as a bioisostere for oxygen or carbonyl groups. Its application allows for the efficient and selective construction of complex fluorinated structures under mild conditions.
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