Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables conjugation to other molecules via click chemistry due to the ethynyl group, facilitating the development of PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. It plays a critical role in linking the E3 ligase binder to a target protein ligand, enabling selective degradation of disease-causing proteins. Also investigated for use in chemical biology tools to study protein function and cellular pathways.