Used as a biomarker in biological samples to assess the activity of cytochrome P450 enzymes, particularly in studies related to arachidonic acid metabolism. Commonly measured in urine and plasma to evaluate cardiovascular diseases, inflammation, and endothelial dysfunction. Plays a role in research on hypertension, diabetes, and kidney disorders due to its connection with eicosanoid pathways. Also utilized in pharmacological studies to monitor the effects of drugs that modulate CYP epoxygenase activity.