4, 5-Dimethyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate
97%
Reagent
Code: #178041
CAS Number
458566-99-9
science Other reagents with same CAS 458566-99-9
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Molecular Information
Weight
326.41 g/mol
Formula
C₁₂H₁₇F₃O₃SSi
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Registry Numbers
MDL Number
MFCD28969391
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Storage & Handling
Storage
Room temperature, seal, dry, light-proof
description Product Description
Used as a key reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its triflate group acts as an excellent leaving group, enabling efficient formation of carbon-carbon bonds. The trimethylsilyl and dimethyl substituents provide steric and electronic stabilization to intermediates, enhancing selectivity and yield in complex molecule construction. Commonly employed in the synthesis of pharmaceuticals, agrochemicals, and advanced materials where precise molecular architecture is required. Stable under a range of reaction conditions, it allows for sequential transformations in multi-step synthetic routes.
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