4, 5-Dimethyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate

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Reagent Code: #178041
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CAS Number 458566-99-9

science Other reagents with same CAS 458566-99-9

blur_circular Chemical Specifications

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Weight 326.41 g/mol
Formula C₁₂H₁₇F₃O₃SSi
badge Registry Numbers
MDL Number MFCD28969391
inventory_2 Storage & Handling
Storage Room temperature, seal, dry, light-proof

description Product Description

Used as a key reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its triflate group acts as an excellent leaving group, enabling efficient formation of carbon-carbon bonds. The trimethylsilyl and dimethyl substituents provide steric and electronic stabilization to intermediates, enhancing selectivity and yield in complex molecule construction. Commonly employed in the synthesis of pharmaceuticals, agrochemicals, and advanced materials where precise molecular architecture is required. Stable under a range of reaction conditions, it allows for sequential transformations in multi-step synthetic routes.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿3,780.00
inventory 250mg
10-20 days ฿5,200.00
inventory 5g
10-20 days ฿48,060.00
inventory 1g
10-20 days ฿14,000.00

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4, 5-Dimethyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate
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Used as a key reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its triflate group acts as an excellent leaving group, enabling efficient formation of carbon-carbon bonds. The trimethylsilyl and dimethyl substituents provide steric and electronic stabilization to intermediates, enhancing selectivity and yield in complex molecule construction. Commonly employed in the synthesis of pharmaceuticals, agrochemicals, and advanced materials where precise molecular architecture is required. Stable under a range of reaction conditions, it allows for sequential transformations in multi-step synthetic routes.
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