Used as a cleavable linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. The compound contains a strained alkyne group that participates in bioorthogonal click chemistry, allowing for selective conjugation under physiological conditions. Its dioxopyrrolidinyl ester functionality facilitates efficient coupling to antibodies or other biomolecules. The polyether chain provides hydrophilicity and flexibility, improving solubility and reducing aggregation in biological environments. Upon internalization into target cells, the linker can be cleaved under specific intracellular conditions, releasing the active drug payload. This makes it valuable in the development of precision oncology therapeutics with improved stability and controlled release profiles.