Dde-D-Dab(Fmoc)-OH
97%
Reagent
Code: #177879
CAS Number
1263046-84-9
science Other reagents with same CAS 1263046-84-9
blur_circular Chemical Specifications
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Molecular Information
Weight
504.583 g/mol
Formula
C₂₉H₃₂N₂O₆
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Registry Numbers
MDL Number
MFCD05663737
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used in solid-phase peptide synthesis, particularly for the construction of complex peptides requiring orthogonal protection strategies. The Dde group serves as a selectively removable protecting group for the side chain of diamino butyric acid (Dab), allowing stepwise assembly without unintended deprotection. The Fmoc group ensures alpha-amino protection during chain elongation, compatible with standard Fmoc-based synthesis protocols. This compound is especially valuable in synthesizing branched or multiply modified peptides, such as those used in drug development, epitope mapping, and peptide-based vaccine design. Its selective deprotection characteristics enable site-specific modifications like biotinylation or fluorescent labeling during peptide synthesis.
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