4-((4-(2,4-Dichlorophenyl)-3-ethylthiazol-2(3H)-ylidene)amino)benzenesulfonamide
99%
science Other reagents with same CAS 2561476-24-0
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Used primarily as a potent carbonic anhydrase inhibitor, this compound exhibits significant diuretic and antiglaucoma activity. It reduces intraocular pressure by inhibiting aqueous humor formation in the ciliary body, making it valuable in glaucoma treatment. It also promotes diuresis by inhibiting carbonic anhydrase in the renal tubules, increasing excretion of sodium, potassium, bicarbonate, and water. Additionally, it has been explored for its anticonvulsant properties and potential in managing altitude sickness due to its ability to induce metabolic acidosis. Its sulfonamide structure enhances binding affinity to carbonic anhydrase isoforms, contributing to high efficacy at low doses.
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