Used as a potent and selective activator of the calcium-activated potassium (KCa) channels, particularly the KCa2.2 and KCa2.3 subtypes. It enhances neuronal hyperpolarization, leading to reduced excitability in nerve cells. This property makes it valuable in research focused on neurological disorders such as epilepsy, neuropathic pain, and neurodegenerative diseases. It is also investigated for its potential in modulating vascular tone and treating conditions related to smooth muscle hyperactivity. Due to its ability to cross the blood-brain barrier, it is useful in central nervous system pharmacology studies.