Dovitinib (TKI-258, CHIR-258)

≥99%

Reagent Code: #77589
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CAS Number 405169-16-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 392.43 g/mol
Formula C₂₁H₂₁FN₆O
badge Registry Numbers
MDL Number MFCD10565680
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Dovitinib is primarily used in the treatment of various cancers due to its ability to inhibit multiple tyrosine kinases, which play a critical role in cancer cell growth and survival. It is particularly studied in renal cell carcinoma (RCC), where it targets pathways like VEGF and FGF, which are often dysregulated in this type of cancer. Additionally, it has shown potential in treating gastrointestinal stromal tumors (GIST) and certain types of breast cancer by blocking signaling pathways that promote tumor progression. Dovitinib is also being explored in combination therapies to enhance its efficacy and overcome resistance to other cancer treatments. Its broad-spectrum kinase inhibition makes it a versatile candidate for targeting multiple oncogenic pathways simultaneously.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance White to beige to yellowish green powder
Purity (%) 99-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿8,145.00

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