SU5204 is a potent and selective inhibitor of protein kinases, particularly known for its activity against Src family kinases and receptor tyrosine kinases such as EGFR and VEGFR. It is widely used in research settings to study signal transduction pathways involved in cell proliferation, survival, and migration. Due to its ability to block key kinases involved in tumor growth and angiogenesis, SU5204 serves as a valuable tool in cancer research, helping to elucidate the role of specific kinases in tumor progression and metastasis. It is also employed in preclinical studies to assess the therapeutic potential of kinase inhibition in various disease models, especially in oncology and inflammatory conditions. Its application extends to in vitro assays and cell-based studies where modulation of kinase activity is required to understand disease mechanisms or evaluate combination therapies.