PDGFR Tyrosine Kinase Inhibitor III
98%
Reagent
Code: #227208
CAS Number
205254-94-0
blur_circular Chemical Specifications
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Molecular Information
Weight
485.53 g/mol
Formula
C₂₇H₂₇N₅O₄
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Storage & Handling
Storage
2-8°C
description Product Description
Used in research to inhibit platelet-derived growth factor receptor (PDGFR) tyrosine kinase activity, this compound helps study signal transduction pathways involved in cell proliferation, migration, and survival. It is applied in cancer research to explore mechanisms of tumor growth and angiogenesis, particularly in tumors driven by PDGFR signaling. Also utilized in studies of fibrotic diseases and atherosclerosis, where PDGFR activation plays a role in tissue remodeling and smooth muscle cell proliferation. Its selectivity makes it a tool compound for distinguishing PDGFR-mediated effects from other kinase-driven processes in cellular and animal models.
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