PDGFR Tyrosine Kinase Inhibitor III

98%

Reagent Code: #227208
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CAS Number 205254-94-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 485.53 g/mol
Formula C₂₇H₂₇N₅O₄
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in research to inhibit platelet-derived growth factor receptor (PDGFR) tyrosine kinase activity, this compound helps study signal transduction pathways involved in cell proliferation, migration, and survival. It is applied in cancer research to explore mechanisms of tumor growth and angiogenesis, particularly in tumors driven by PDGFR signaling. Also utilized in studies of fibrotic diseases and atherosclerosis, where PDGFR activation plays a role in tissue remodeling and smooth muscle cell proliferation. Its selectivity makes it a tool compound for distinguishing PDGFR-mediated effects from other kinase-driven processes in cellular and animal models.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿9,830.00
inventory 25mg
10-20 days ฿37,060.00

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