TrkA-IN-1 is primarily utilized in research settings to study the role of TrkA receptors in cellular processes. It serves as a selective inhibitor of TrkA kinase activity, making it a valuable tool for investigating signaling pathways involved in neuronal development, survival, and function. Researchers use this compound to explore its potential in understanding and treating conditions related to TrkA dysregulation, such as certain cancers and neuropathic pain. Additionally, it aids in the development of targeted therapies by providing insights into the mechanisms of TrkA inhibition. Its application extends to preclinical studies, where it helps evaluate the efficacy and safety of novel therapeutic agents targeting TrkA-related pathways.